I had trouble using Flatseal to adjust permissions for Flatpak applications in Linux Mint. But that was a few months ago and may have been fixed. Other than that I never really had trouble with stuff being broken or unavailable in Mint.

I guess if you use very new hardware you might prefer a newer kernel than the one Mint uses. Or if you want the latest versions of packages, a rolling distro might suit you better. Or you might prefer a different filesystem. But if none of this bothers you, there’s no need to switch. Mint generally works well.